Most career INTs vs. Philip Rivers? Bucs' Brent Grimes
The Bucs only face AFC opponents once every four years, so even an 11-year starter like Philip Rivers has a limited history against Tampa Bay -- he threw four touchdowns and zero interceptions in a San Diego win in Tampa in 2008, then threw for another three (but two INTs) in a 2012 loss in Tampa.
Cornerback Brent Grimes has a much more recent -- and successful -- history against Rivers, having not only played against him in each of the last three years with the Dolphins, but having gotten interceptions in all three games. He has four total INTs against Rivers, which ranks as the most he has against any NFL quarterback, and the most that anyone has picked off Rivers in his 147 career interceptions.
Normally, such an honor with a quarterback who's only played with one team would have to go to a division rival -- he's now faced the Raiders, Broncos and Chiefs close to 20 times each, and yet Grimes, in three career games, has four interceptions, all since the 2013 season.
To chart Grimes' 28 career interceptions is an amusing chore, showing the randomness of who a cornerback will line up against over the course of a decade in the NFL. Grimes has four INTs against Rivers, three against former Bucs QB Josh Freeman, and two each against Drew Brees (who he'll face twice in the next four games) and Mark Sanchez. The list of guys he's picked off once is both impressive -- Cam Newton, Tony Romo, Andrew Luck, Eli Manning, Matt Stafford, Joe Flacco, as well as young guys like Marcus Mariota, Kirk Cousins and Derek Carr, and then also completely obscure names like Matt Simms, Tyler Thigpen and Brian Brohm.
Another guy who knows the Chargers well is defensive end Robert Ayers, who opened his career with the Broncos and faced them twice a year. Ayers has never lost at Qualcomm -- 4-0 all-time -- and has a playoff win against Rivers and San Diego as well, from 2013. He's 6-3 all-time against the Chargers, and had a sack and forced fumble against Rivers in 2011.