Monday, April 23, 2018

Identical twins will be part of space study

CAPE CANAVERAL — When astronaut Scott Kelly embarks on a one-year space station stint next spring, his twin brother will be offering more than his usual moral support.

Retired astronaut Mark Kelly will be joining in from Earth, undergoing medical testing before, during and after his brother's American-record-setting flight.

It's part of an unprecedented study of identical twins, courtesy of the Kellys and NASA. Researchers hope to better understand the effects of prolonged weightlessness by comparing the space twin with the ground twin.

The Earthbound Kelly draws the line, though, at mimicking his brother's extreme exercise regimen while in orbit or eating "crappy space station food."

"It's not bad when you're in space," Mark said. But he won't be carrying around "a can of Russian lamb and potatoes when I'm out to eat with my friends."

As for matching his brother's 1½ to 2 hours of daily exercise, Mark replied with a mutinous chuckle, "Sure, I'll try. No problem."

This is the genetic double, mind you, of the 50-year-old astronaut who has volunteered to spend an entire year aboard the International Space Station beginning next March, along with Russian cosmonaut Mikhail Kornienko, 54, a former paratrooper.

No American has come close to a year; seven months is NASA's max for a single human mission. The Russians, on the other hand, are old hands at long-duration spaceflight, claiming title to a record-setting 14½-month mission back in 1994-95.

"No second thoughts — I'm actually getting kind of excited about the whole idea as we get closer," Scott said in a recent interview with the Associated Press.

Reaction from others has varied from "  'Oh, that would be really cool to be in space for a year' to 'What, are you out of your mind?' " he said with a laugh.

Scott knows what he's getting into. He spent five months on the orbiting lab in 2010-2011. He began counting down the days on Twitter in late March.

Eager to explore new medical territory, Scott offered to have a pressure sensor drilled into his skull to study the impaired vision experienced by some long-term space fliers.

He has also volunteered for spinal taps in orbit. He'll share quarters at one point with an emergency medical doctor-turned-NASA astronaut. The space station crew typically numbers six.

"As a test pilot, I like to push the envelope on things, and, in this case, I feel like I'm maybe trying to push the envelope on data collection as well," explained Scott, a retired Navy captain.

But NASA scientists insist there's no compelling need for implants and spinal taps. They admire his gung-ho attitude, though, and marvel at their good fortune in having a set of identical twins for comparison.

The Kellys represent a scientific gift, said Craig Kundrot, deputy chief scientist for the human research program at NASA's Johnson Space Center in Houston.

"Not only are they the same genetically, but one is an astronaut, (and) one's a retired astronaut. So they've followed very similar career paths. After Scott's mission is done, he'll have 540 days of spaceflight (in four missions). Mark will have 54 — so exactly a 10-fold difference," Kundrot said.

"That's just an uncanny opportunity that we're taking advantage of."

NASA has selected 10 proposals for the twin study, involving the immune system, gut bacteria, reaction time, fluid shift in space and its potential connection to visual impairment, DNA and RNA molecular science, and hardening of the arteries, among others. The researchers will receive a combined $1.5 million from NASA over three years.

A Stanford University sleep specialist and immunologist, Dr. Emmanuel Mignot, wants to give each brother a standard flu shot before, during and after the one-year mission. Blood draws will highlight any differences between the space twin and the ground twin and will help researchers better understand changes to the body's immunity in weightlessness.

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