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Study: Y chromosome evolves faster than rest

WASHINGTON — Women might think of men as primitive, but new research indicates the Y chromosome — the thing that makes a man male — is evolving far faster than the rest of the human genetic code.

A new study comparing the Y chromosomes from humans and chimpanzees, our nearest living relatives, show they are about 30 percent different. That is far greater than the 2 percent difference between the rest of the human genetic code and that of the chimp's, according to a study appearing online Wednesday in the journal Nature. These changes occurred in the past 6 million years or so, relatively recently when it comes to evolution.

"The Y chromosome appears to be the most rapidly evolving of the human chromosomes," said study co-author Dr. David Page, director of the prestigious Whitehead Institute in Cambridge and a professor of biology at MIT. "It's an almost ongoing churning of gene reconstruction. It's like a house that's constantly being rebuilt."

Before men get too impressed with themselves, lead author Jennifer Hughes offers words of caution: Just because the Y chromosome, which determines gender, is evolving at a speedy rate it doesn't necessarily mean men themselves are more evolved.

Researchers took the most detailed examination of the Y chromosome, which females do not have, of both humans and chimps and found entire sections dramatically different. There were even entire genes on the human Y chromosome that weren't on the chimp, said Hughes, also of the Whitehead Institute.

The two-year research took twice as long as expected because of the evolutionary changes found, Hughes said.

There is a bit of a proviso to the comparison to other chromosomes. While all human and chimp chromosomes have been mapped, only two chimp chromosomes have been examined in great detail: Y and chromosome 21. But there's still enough known to make the claim that the Y is the speediest evolver, Hughes and Page said.

Study: Y chromosome evolves faster than rest 01/13/10 [Last modified: Wednesday, January 13, 2010 10:41pm]

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