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Bone drugs may lead to fractures in rare cases, FDA warns

Washington

FDA warns of fractures with bone drugs

The Food and Drug Administration warned Wednesday that patients taking widely used drugs designed to prevent broken bones may, paradoxically, be at increased risk for certain unusual fractures of the thigh bone. The FDA warning is about drugs known as biophosphonates, which are commonly used to treat osteoporosis. The FDA is requiring that drug companies add a warning to the labels of Fosamax, Fosamax Plus D, Actonel, Actonel with Calcium, Boniva, Atelvia, and Reclast. The FDA said patients taking bisphosphonates for osteoporosis should not stop using their medication unless their doctor tells them to. But they should report any new thigh or groin pain to their doctor so they can be evaluated for a possible thigh fracture, the agency said.

Elsewhere

Beijing: A group of retired Communist Party officials and intellectuals issued a blunt demand Tuesday for total press freedom in China, stating that the current climate of censorship and government control of the press violated China's Constitution and debased the government's claim to represent its citizens.

Rotterdam, Netherlands: The United States denounced a Dutch court's decision Wednesday to grant an early release to Wesam al-Delaema, a Dutch citizen of Iraqi origin who had been sentenced in 2006 to 25 years in prison for conspiring to kill Americans in Iraq.

Veszprem, Hungary: The Hungarian aluminum plant behind a huge toxic mud spill is to restart operation by Friday, disaster management chief Gyorgy Bakondi said Wednesday.

Manama, Bahrain: Twenty three Shiite activists have been charged with terrorism and conspiring against the government, Prosecutor General Abdul-Rahman al-Sayed said Wednesday.

Brisbane, Australia: A tip from U.S. officials led to the seizure of more than 1,000 pounds of cocaine transported from South America, police said today.

Times wires

Bone drugs may lead to fractures in rare cases, FDA warns 10/13/10 [Last modified: Wednesday, October 13, 2010 10:59pm]
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