Colts (5-3) at Jaguars (1-7)
When/where: 8:20; EverBank Field, Jacksonville
TV/radio: NFL Network; 98.7-FM, 1010-AM
Line/OU: Colts by 3; 42½
The lightning-fast development of Colts rookie QB Andrew Luck makes the sluggish growth of Jaguars second-year QB Blaine Gabbert even more exasperating. Luck has positioned the Colts, winners of two games in 2011, for a run at the playoffs. He hasn't fared as well on the road as at home. But with some help from his defense against the impotent Jaguars offense — star running back Maurice Jones-Drew is hurt — he pulls this one out.
Stephen F. Holder's pick: Colts 24, Jaguars 20