LOS ANGELES — Kenjon Barner rushed for a school-record 321 yards and five touchdowns and Marcus Mariota threw four TDs as No. 2 Oregon produced another landmark offensive game in a 62-51 victory Saturday night over No. 18 Southern California.
Josh Huff caught two touchdowns, and De'Anthony Thomas and Daryl Hawkins also caught scoring passes for the Ducks, who outlasted USC to extend their winning streak to 12 since the Trojans won in Eugene last season.
Oregon's 730 yards and 62 points were the most ever allowed by USC, which began playing football in 1888.
Barner set a rushing record for a USC opponent by the third quarter, topping Curtis Enis' 241 yards for Penn State in 1996, and smashed the school record shortly afterward as the Ducks gradually pulled away in their closest game of the year.
Matt Barkley passed for 484 yards and four touchdowns while hitting Marqise Lee with 12 passes for 157 yards and two touchdowns for the Trojans.
Freshman receiver and former Berkeley Prep star Nelson Agholor led USC in receiving yards with 162 on just six catches and his first college touchdown, a 76-yard reception in the second quarter. He came into the game with eight catches on the season.
But the preseason No. 1 team hit a defensive nadir not even matched during Pete Carroll's final season in 2009, when several opponents destroyed the Trojans' defense.
Barner has already roared past Barkley in the Heisman Trophy race, and the product of Riverside, Calif., entertained his friends and family members at the Coliseum with another dominant ground performance, capped by enthusiastic celebrations of every touchdown.
Mariota carved up the Trojans for 304 yards passing, going 20 for 23 without an interception and rushing for 96 yards.
USC harassed Darron Thomas into a sub-par performance in this matchup last season, but the freshman who has replaced him showed no nerves in the historic stadium while playing against the team expected to be Oregon's biggest Pac-12 obstacle.
Oregon, which could move up in the BCS standings after this win and Notre Dame's narrow victory, had won every game this season by at least 17 points. USC's offense did its part, scoring more points and gaining more yards (615) than Oregon had allowed all year.