Colts (6-3) at Titans (4-5)
When/where: 8:25; LP Field, Nashville
TV/radio: NFL Network; 98.7-FM, 1010-AM
Line/OU: Colts by 3; 42½
Indianapolis has won eight of nine in the series and is 3-1 on the road this year but is coming off a 38-8 home loss to the Rams. The Titans won't have injured QB Jake Locker, so Ryan Fitzpatrick starts after throwing two touchdown passes in Sunday's 29-27 loss to the Jaguars. In Nashville a year ago, Indianapolis QB Andrew Luck led an 80-yard touchdown drive to force overtime then another touchdown drive to win it. Colts RB Donald Brown has 241 yards in his past two games against the Titans.
Greg Auman's pick: Colts 27, Titans 21
Colts — Out: CB Josh Gordy (groin), S Delano Howell (neck), CB Greg Toler (groin). Probable: NT Josh Chapman (knee), G Mike McGlynn (thumb).
TITANS — Out: CB Tommie Campbell (shoulder), LB Moise Fokou (knee), C Brian Schwenke (ankle), WR Damian Williams (hip). Questionable: LB Zaviar Gooden (hamstring). Probable: T David Stewart (shoulder), G Chance Warmack (ankle).