Chiefs (2-0) at Eagles (1-1)
When/where: 8:25; Lincoln Financial Field, Philadelphia
TV/radio: NFL Network; 1010-AM
Line/OU: Eagles by 3; 51
Coach Andy Reid makes a quick return to Philadelphia, having led Kansas City to as many wins as in all of 2012. The Chiefs were the league's lowest-scoring team last season. Their 28 points in a Week 1 win against Jacksonville were more than in any game in 2012. How underappreciated is Chiefs QB Alex Smith? He's 21-5-1 as a starter since the start of 2011 with 34 touchdowns and 10 interceptions. Eagles RB LeSean McCoy is thriving in first-year coach Chip Kelly's offense, leading the NFL with 356 yards from scrimmage. This will come down to turnovers. Kansas City is plus-4, Philadelphia plus-3.
Greg Auman's pick: Eagles 31, Chiefs 27