Packers (10-0) at Lions (7-3)
12:30 p.m., Ch. 13
Line; O/U: Packers by 6; 551/2
The undefeated Packers look a little vulnerable after Sunday's toughie against the Bucs. Their opponents' formula seems to be run well and keep the ball away from QB Aaron Rodgers, and when he does get possession, force him to make tough throws against tight man-to-man coverage. Rodgers had 11 incomplete passes against the Bucs on Sunday, his most since Oct. 9 against the Falcons. The Lions haven't shown enough consistency running the ball, but they rank fifth in pass defense.
Holder's pick: Packers 34, Lions 24
Dolphins (3-7) at Cowboys (6-4)
4:15 p.m., Ch. 10
Line; O/U: Cowboys by 7; 44
Miami has averaged 28.6 points in its past three games, all wins, so the Dolphins might have the ability to make some plays against a talented Cowboys defense. During their three-game winning streak, the Dolphins have held the Chiefs, Redskins and Bills to single digits in scoring. The Cowboys have a bit more offensive firepower, though, and QB Tony Romo is undefeated on Thanksgiving Day. The Cowboys' offensive balance could be the difference.
Holder's pick: Cowboys 27, Dolphins 21
49ers (9-1) at Ravens (7-3)
8:20 p.m., NFL Network
Line; O/U: Ravens by 31/2; 381/2
Isn't family supposed to get together on Thanksgiving? This family affair pits 49ers coach Jim Harbaugh against brother and Ravens coach John, and this is a very big test for both teams. It's a matchup of teams with similar styles and strengths. Both want to run the ball and play stout defense. This game feels like a tossup. So we'll go with the home team.
Holder's pick: Ravens 23, 49ers 21
Stephen F. Holder, Times staff writer