Seahawks (4-2) at 49ers (4-2)
When/where: 8:20; Candlestick Park, San Francisco
TV/radio: NFL Network; 98.7-FM, 1010-AM
Line/OU: 49ers by 7; 37½
It shapes up to be an interesting ride down the stretch in the NFC West. After six games, these two clubs seem on course for a seasonlong fight. Tonight, it's hard to envision Seahawks QB Russell Wilson having the same success he did in a rally over the Patriots on Sunday (16-of-27 for 293 yards and two late TDs). The 49ers defense, though coming off a poor performance in a loss to the Giants, present a stiffer test. And the prideful 49ers take after their coach, Jim Harbaugh. A bounceback seems likely.
Stephen F. Holder's pick: 49ers 23, Seahawks 21