CINCINNATI — Brayan Pena's pinch-hit single in the eighth inning completed another late rally by the Reds, who overcame more injuries on Friday and beat the Pirates 6-5 to keep their momentum going toward the All-Star break.
Down 5-1 after six innings, the Reds scored twice with the help of third baseman Pedro Alvarez's throwing error in the seventh and added three more in the eighth.
Cincinnati is 7-2 on its 11-game homestand leading into the break.
Devin Mesoraco homered with two outs off left-hander Tony Watson in the eighth, and the Reds put together four more singles, with RBI hits by Ramon Santiago and Pena completing Cincinnati's second big comeback of the week.
Curtis Partch, called up earlier in the day, escaped a bases-loaded threat in the eighth.
Aroldis Chapman fanned the side in the ninth for his 20th save in 22 chances. He has at least one strikeout in his past 40 appearances, passing Bruce Sutter for the record by a major-league reliever since 1900.
Andrew McCutchen and Pedro Alvarez homered for a 4-0 lead off Cincinnati's Mat Latos, who left after five innings with back spasms. It was the shortest of his six starts since returning from torn knee cartilage and a strained pitching forearm.
The Reds have been hit hard by injuries in the past week.
First baseman Joey Votto is on the DL indefinitely with a thigh injury. Second baseman Brandon Phillips tore a ligament in his left thumb and had surgery on Friday. Skip Schumaker was expected to help fill in at second base, but he went on the seven-day concussion list.
Starter Homer Bailey slightly strained his right knee Thursday, but is expected to make his next turn.
Billy Hamilton had a sore hamstring Thursday and was relegated to pinch-hitting. He was back in the lineup Friday and produced a run right away. He led off with a bunt toward first baseman Gaby Sanchez, dodged the tag then lunged for the base, touching it safely with his hand. He scored from first on Zack Cozart's double.