NEW YORK — Andy Roddick held on to avoid a first-round upset at the U.S. Open, beating 96th-ranked Michael Russell 6-2, 6-4, 4-6, 7-5 Wednesday night.
The 21st-seeded Roddick, who won the 2003 U.S. Open, had a 13-0 edge in aces in the all-American matchup. After breezing through the first two sets, he ran into trouble in the third, then fell behind by a break in the fourth. But Roddick broke right back to even that set at 3-all.
"It was okay. … I'm still trying to find myself," Roddick said. "I'm certainly still short on match play this year. I'll keep fighting because it's what I do. I don't care if it's ugly; I'll try to get through.
"I'm not going to pretend that I am in championship form right now, (but) people have worked their way into tournaments before, and I'll get that opportunity. I don't have to win the tournament tomorrow; I just have to win my next match."
Roddick, who turned 29 on Tuesday, faces 18-year-old Jack Sock of the United States next.
Russell fell to 0-7 at Flushing Meadows.
Also advancing to Round 2 was Tampa resident John Isner, who beat Marcos Baghdatis 7-6 (7-2), 7-6 (13-11), 2-6, 6-4. Isner's next match is against another American, Robby Ginepri, who also won Wednesday.
On the women's side, No. 12 seed Agnieszka Radwanska became the eighth seed to bow out in three days, losing 6-3, 4-6, 6-3 to Angelique Kerber. Other seeded losers Wednesday included No. 8 Marion Bartoli, No. 14 Dominika Cibulkova and No. 20 Yanina Wickmayer, a 2009 semifinalist.
In the day's late match, third seed Maria Sharapova rolled over Anastasiya Yakimova 6-1, 6-1.
Other women's winners included Tampa resident Sam Stosur, the ninth seed.
The biggest upset was in men's doubles. Top-ranked Bob and Mike Bryan, Wesley Chapel residents, lost a first-round match at a Grand Slam tournament for the first time since the 2001 Australian Open. Unseeded Ivo Karlovic and Frank Moser beat the twins 6-4, 2-6, 6-2.
The Bryans had won three of the past four major titles, tying the Open era record with their 11th Grand Slam championship this summer at Wimbledon. They struggled against the 6-foot-10 Karlovic's powerful serve.
"It was an awkward matchup," Mike said. "And we're never really playing our best tennis early in these Grand Slams."
Bartoli lost to 19-year-old American Christina McHale and Cibulkova to Irina Falconi, a 21-year-old American who went to Georgia Tech. Both advanced to the third round at a Grand Slam for the first time.
Falconi pulled an American flag out of her bag after the match.
"I've heard so much about media talking about American tennis, and I really wanted to portray that there's a huge wave of American players," she said. "I strongly believe in all that is USA, and I wanted to represent it and show the world that it's coming. It's coming. No need to wait any longer."
Among the other winners were 2009 U.S. Open champion Juan Martin del Potro, who didn't try to defend his title last year because of a wrist injury, and No. 4 Andy Murray. No. 10 Nicolas Almagro became the highest-seeded man to lose.
Two-time French Open semifinalist Robin Soderling pulled out shortly before his first-round match, citing stomach pain and a headache.