Even without Shea Ralph and Svetlana Abrosimova, Connecticut opened defense of its NCAA title with a record performance.
Swin Cash had 12 points and 16 rebounds Saturday night as top-ranked UConn cruised to a 101-29 win over Long Island University in the first round of the East Region, the best defensive performance in women's NCAA Tournament history.
UConn eclipsed Colorado's 78-34 win over Southwest Missouri State in 1995.
UConn's victory margin tied the second largest in tournament history. Tennessee beat North Carolina A&T 111-37 in 1994.
The Huskies are without their two All-Americans, sidelined with season-ending injuries. But their teammates had no problems with the much smaller Blackbirds.
Tamika Williams was 6-of-6 from the floor and finished with 12 points. Sue Bird and Diana Taurasi combined for 25 points and 12 assists for the top-seeded Huskies.
It was a rough tournament debut for the Blackbirds, who suffered the worst loss in school history. No opponent had scored more than 92 against them. They shot 15 percent from the floor, hitting 10 of 65 attempts, and committed 19 turnovers.
SW MISSOURI ST. 89, TOLEDO 71: Tara Mitchem scored a career-high 40 and the Bears overcame a rare subpar game by Jackie Stiles in Piscataway, N.J.
Stiles, the NCAA's all-time leading scorer, had a season-low 13 points before leaving with about nine minutes left after being knocked woozy when she was hit in the temple running into a pick at midcourt.
The senior guard, who averaged 30.7 points this season, lay on the floor for about 20 seconds before being helped to the bench. Team doctor Brian Mahaffey did not say whether she suffered a concussion, but he said he expected her to be fine.