When/where: 8:25; University of Phoenix Stadium, Glendale, Ariz.
TV/radio: NFL Network; 98.7-FM, 1010-AM
Line/OU: Seahawks by 61/2; 401/2
Arizona's challenge? Carson Palmer has thrown 11 interceptions (only the Giants' Eli Manning has more), and Seattle is plus-7 in turnovers, including nine picks. CB Richard Sherman has four picks over his past three games against Arizona, which has its own dangerous cornerback in Patrick Peterson. Last season, the Seahawks beat the Cardinals 58-0.
Greg Auman's pick: Seahawks 34, Cardinals 17