New York Mayor Bill de Blasio speaks during a virtual news conference last week.
The strictest vaccine mandate in the U.S. will take effect Dec. 27. The goal is to prevent a spike in COVID-19 infections during the holidays.
Are two doses enough to be considered fully vaccinated for COVID-19? Should boosters be included?
Soon, travelers entering the U.S. will have to show they tested negative for COVID-19 before boarding their flight.
New York, once a global epicenter, has the country’s biggest contact tracing effort.


  1. A man walks off a vaccination bus at a mobile vaccine clinic in Midtown Manhattan on Dec. 6. As COVID science evolves, "we will look at whether we need to update our definition of ‘fully vaccinated,’ ” said the CDC’s director, Rochelle Walensky.
  2. A view of the University of Florida from the campus entrance at W University Avenue and SW 13th Street in Gainesville.
  3. New York Mayor Bill de Blasio speaks during a virtual news conference last week.
  4. A COVID-19 test center operates inside the Tom Bradley International Terminal at Los Angeles International Airport on Dec. 1 in Los Angeles.
  5. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, speaks during a daily briefing at the White House earlier this month.
  6. The Louisiana Department of Health said at least 10 people on the Norwegian Cruise Line ship tested positive for COVID-19.
  7. A group of anti-abortion protesters pray together in front of the U.S. Supreme Court last week.
  8. Contact tracer Alejandra Camarillo works in June at a Harris County Public Health facility in Houston.
  9. A sign is posted outside a CVS pharmacy on Thursday in Indianapolis. A rush of vaccine-seeking customers and staff shortages are squeezing drugstores around the country. That has led to frazzled workers and even temporary pharmacy closures.
  10. Florida's weekly coronavirus numbers.
  11. An Orange Farm, South Africa, resident receives her jab against COVID-19 on Friday at the Orange Farm multipurpose center. South Africa has accelerated its vaccination campaign a week after the discovery of the omicron variant of the coronavirus.
  12. A woman receives a dose of a COVID-19 vaccine at a center, in Soweto, South Africa, on Nov. 29. The emergence of the new omicron variant and the world’s desperate and likely futile attempts to keep it at bay are reminders of what scientists have warned for months: The coronavirus will thrive as long as vast parts of the world lack vaccines.
  13. Consumer watchdogs are warning of an uptick in holiday scams this season.
  14. Members of the Florida House of Representatives work during a legislative session, Friday, April 30, 2021, at the Capitol in Tallahassee, Fla. (AP Photo/Wilfredo Lee)
  15. A vaccination sticker seen while the residents and staff at the Toby & Leon Cooperman Sinai Residences in Boca Raton received their Pfizer booster shots in September.
  16. President Joe Biden speaks in the South Court Auditorium on the White House campus Wednesday in Washington.
  17. In this Nov. 20 file photo, a man takes part in a demonstration against the country's coronavirus restrictions in Vienna, Austria. The  omicron variant kept a jittery world off-kilter Wednesday, as reports of infections linked to the mutant strain cropped up in more parts of the globe, and one official said that the wait for more information on its dangers felt like “an eternity.”
  18. Licensed practical nurse Yokasta Castro, of Warwick, R.I., draws a Moderna COVID-19 vaccine into a syringe at a mass vaccination clinic on May 19 at Gillette Stadium, in Foxborough, Mass. While all eyes are on the new and little-understood omicron variant, the delta form of the coronavirus isn't finished wreaking havoc in the U.S. There is much that is unknown about omicron, including whether it is more contagious than previous versions, makes people sicker or more easily thwarts the vaccine or breaks through the immunity that people get from a bout of COVID-19.
  19. This artist sketch depicts Center for Reproductive Rights Litigation Director Julie Rikelman speaking to the Supreme Court, Wednesday, Dec. 1, 2021, in Washington. Seated to Rikelman's right is Solicitor General Elizabeth Prelogar.  Justices seated from left are Associate Justice Brett Kavanaugh, Associate Justice Elena Kagan, Associate Justice Samuel Alito, Associate Justice Clarence Thomas, Chief Justice John Roberts, Associate Justice Stephen Breyer, Associate Justice Sonia Sotomayor, Associate Justice Neil Gorsuch and Associate Justice Amy Coney Barrett. (Dana Verkouteren via AP)
  20. The South Unit of the Central Florida Reception Center in Orlando. The Florida Department of Corrections and Disability Rights Florida have reached a settlement that will add accommodations for prisoners with disabilities.
  21. In this Sept. 29, 2020, photo, President Donald Trump looks at his face mask during the first presidential debate at Case Western University and Cleveland Clinic, in Cleveland, Ohio. A book by Donald Trump's ex-chief of staff says Trump tested positive for COVID-19 three days before his first debate in September 2020.
  22. Anthony Fauci, Director of the National Institute of Allergy and Infectious Diseases and Chief Medical Advisor to the President, speaks alongside U.S. President Joe Biden as he delivers remarks on the Omicron COVID-19 variant following a meeting of the COVID-19 response team at the White House on Monday.
  23. CBD oil in a bottle with dropper May 7, 2021 in St. Petersburg.