As expected, the Bucs will start Ted Larsen at center and move Jeremy Zuttah to left guard, part of the offensive line shuffle to replace injured All-Pro guard Carl Nicks.
It's a similar look to what Tampa Bay showed last season when Nicks underwent toe surgery, and they started to experiment with it in practice this past week.
As for inactives, there are no surprises, with RB Jeff Demps (groin), Nicks, DT Derek Landri, DE Steven Means, WR Skye Dawson, CB Deveron Carr and G Patrick Omameh out for the Bucs.
For the Falcons, they'll be without two of their top weapons, as WR Roddy White and RB Steven Jackson. RB Jacqquiz Rodgers will start for Jackson. Atlanta is also without WR Julio Jones, their best receiver.