5 Best Weight Loss Pills and Diet Supplements That Actually Work

Experiencing scale shock? If diet and exercise aren't getting the job done, consider adding one of these weight loss supplements.
Experiencing scale shock? If diet and exercise aren't getting the job done, consider adding one of these weight loss supplements. [ Stock ]
Published Nov. 24, 2021

With the sheer number of options available on today’s market, finding the best supplements to help you achieve your fitness goals can be overwhelming. Sometimes, diet and exercise are just not enough to get rid of stubborn body fat. If you’re tired of putting in hours at the gym to no avail, taking a weight loss supplement can provide that extra boost of energy you need to lose a few pounds and see some great results.

There’s just one problem: How do you know which weight loss pill is the best one? To help you find a successful weight loss aid, we reviewed the five best diet pills for 2021. So, without further ado, let’s dive right in.

The 5 Best Weight Loss Pills on the Market

1) PhenQ: Best Weight Loss Supplement Overall

PhenQ is an effective fat burner with premium-grade ingredients, and it made our list as the best overall weight loss pill. It’s ideal as a general fat burner supplement and is even more effective when combined with proper diet and regular exercise.

PhenQ targets weight loss in five different ways:

1) Burns Fat: PhenQ boosts your body’s thermogenic and metabolic rates to increase the speed at which you burn fat and lose weight.

2) Blocks Fat Production: The ingredients in PhenQ are proven to help your body in the process of blocking fat production.

3) Boosts Energy: One of the most common side effects of dieting is fatigue. PhenQ is full of ingredients that provide long-term, sustainable energy throughout the day.

4) Suppresses Appetite: PhenQ also is an effective appetite suppressant, helping quash cravings between mealtimes.

5) Improves Mood: Another common side effect from dieting (especially crash dieting) is mood swings and irritability. PhenQ contains gentle mood-boosting ingredients to ensure you’re feeling good about yourself and have the confidence to get through your day.

PhenQ is one of the most effective weight loss supplements because it contains ingredients scientifically proven to help people lose weight. It speeds up fat loss and increases muscle mass—all with no harsh side effects. If that doesn’t convince you, take a look at some key statistics of PhenQ:

  • Users saw an average increase of 3.80% in muscle mass gains
  • Users lost an average of 7.24% of body fat
  • Users lost an average of 3.44% of body weight

The ingredients of PhenQ include:

  • α-Lacys Reset
  • Capsimax powder (capsicum, piperine, caffeine, and niacin)
  • Chromium picolinate (natural mineral)
  • Caffeine
  • Nopal cactus
  • L-carnitine fumarate (natural amino acid)

PhenQ isn’t a prescription weight loss pill, so you won’t need to see a doctor to buy it. Instead, just head right to the manufacturer’s website if you want to make a purchase.

The company offers free shipping, money-saving multi-buy discounts, and a money-back guarantee valid for 60 days after your purchase. The all-natural ingredients are 100% vegan and vegetarian friendly, and it’s safe for both men and women.

Click Here for the Lowest Price on PhenQ

2) Leanbean: Best Diet Pills for Women

Because men and women have different bodies, it only makes sense that weight loss pills for women and men should have different formulas. Leanbean is the most effective weight loss supplement for women with a hassle-free regimen that produces real results.

The creators of Leanbean designed the fat-burning supplement to enhance a low-fat diet and active lifestyle. When taken properly, it provides numerous weight loss benefits and a big energy boost, but without the stimulants or dangerous side effects.

Supports Fat Metabolism: Leanbean contains a combination of natural minerals, choline, and thermogenics that boost metabolism and get your body working overtime to burn fat and give you more muscle tone and definition.

Suppresses Appetite and Cravings: The star ingredient in Leanbean is glucomannan, which is scientifically proven to be an effective way to reduce appetite. Leanbean uses a higher amount of glucomannan than many of the other top weight loss pills, containing a daily dose of three grams.

Boosts Energy and Focus: Feeling exhausted all the time can be an obstacle to regular exercise and a healthy lifestyle. Leanbean contains a unique combination of vitamins and minerals that boost energy and give you greater focus throughout your day.

Leanbean is a great way to lose weight without ingesting a hefty dose of stimulants, as the formula features a combination of 11 different low-stimulant alternatives.

The main ingredient, glucomannan, swells in your stomach after you ingest it, causing you to feel fuller between meals and reducing calorie intake. In addition, the mineral chromium picolinate stabilizes your metabolism while zinc boosts carbohydrate and fatty acid production.

The creators of Leanbean have packed these weight loss pills for women full of scientifically proven ingredients to get you burning fat and on your way to a healthier and slimmer body. The complete list of ingredients includes:

  • 3000mg of glucomannan
  • Choline (essential nutrient)
  • Chromium picolinate (trace mineral)
  • Vitamin B6
  • Vitamin B12
  • Chloride (electrolyte)
  • Zinc (essential for immune system function)
  • Green coffee bean extract
  • Turmeric (caffeine alternative)
  • Garcinia cambogia (for hydroxycitric acid)
  • Acai berry (antioxidant)
  • Piperine (black pepper extract)

The Leanbean formula is 100% vegan-friendly and features premium ingredients combined in an FDA-approved facility to ensure high quality.

If you want to try Leanbean risk-free, you’ll need to purchase a four-month supply. If you don’t see results by the end of those four months, you can request a full refund under the money-back guarantee. Plus, you won’t get roped into any subscriptions. Leanbean will only charge your card when you decide to make a purchase.

Click Here for the Lowest Price on Leanbean

3) PrimeShred: Best Thermogenic Fat Burner for Men

Next on our list is PrimeShred, our choice as the best weight loss supplement for men. The exclusive formula is so effective because it causes body cells containing fat to break down. Once the cells break down, it triggers your body to flush the fat naturally and speeds up weight loss for maximum benefit.

The PrimeShred formula has a triple boost of benefits:

Destroys Fat: The process of breaking down fat cells in the body is called lipolysis. PrimeShred contains scientifically proven ingredients that stimulate lipolysis, getting rid of those stubborn fat pockets that are so resistant to diet and exercise.

Enhances Energy Naturally: Not all diet pills can increase energy naturally without stimulants, which can cause side effects like shakiness or jitters. PrimeShred is fortified with green coffee and tea, Rhodiola rosea, and L-theanine, which enhance and smooth out the natural effects of caffeine for increased energy and mental clarity.

Speeds Up the Fat-Burning Process: PrimeShred contains cayenne pepper, chlorogenic acid, vitamins B3, B6, and B12, and L-tyrosine, all of which are proven to boost metabolism and promote fat burning.

When you eat too many calories and don’t burn them off with exercise, you’re inevitably going to see some weight gain. When that happens, your body stores the extra fat in cells, which means they’re unavailable to be used as energy.

When you take PrimeShred, the ingredients trigger lipolysis, which is the process of burning fat for energy. They cause the fat cells to break down and release the stored fat, making it available for your body to burn as fuel. As a result, you’ll see an overall reduction in body fat and tighter muscle definition.

The complete ingredient list for PrimeShred includes:

  • 300mg L-tyrosine
  • 500mg green tea extract
  • 150mg DMAE
  • 100mg green coffee
  • Vitamin B complex
  • 250mg L-theanine
  • 5mg BioPerine
  • 250mg Rhodiola rosea root
  • 200mg cayenne pepper
  • 225mg caffeine anhydrous
  • Vegetable capsule

PrimeShred is 100% free of animal-derived substances, making it meat-, egg-, and dairy-free. The formula is also GMO-, soy-, and gluten-free and doesn’t contain artificial sweeteners, colors, or preservatives. You can usually find package deals and multi-buys on the PrimeShred website, such as “buy three bottles, get two free.”

PrimeShred also has a money-back guarantee, which the company will honor as long as you purchase more than a one-month supply. Make sure to claim your refund within 100 days of receiving your order.

Click Here for the Lowest Price on PrimeShred

4) PhenGold: Best Metabolism Booster

PhenGold is the best diet pill on our list for boosting metabolism. The formula boasts maximum-strength ingredients to help you burn fat, lose weight, and keep the weight off for good without any harmful side effects.

Promotes Rapid and Natural Weight Loss: The ingredients in PhenGold trigger specific fat-burning hormones in the body. The supplement eliminates stubborn body fat, even with a healthy diet and regular exercise.

Boosts Metabolism to Burn Fat 24/7: Without a fast metabolism, you won’t be able to get rid of fat and lose weight. The ingredients in PhenGold increase the body’s natural metabolic rate, which means you’ll be able to burn fat around the clock and at a much faster speed, too.

Suppresses Appetite and Curbs Cravings: The clinically proven ingredients in PhenGold will make you feel fuller between meals and curb your cravings.

These weight loss pills work by stimulating your metabolism and speeding up the rate at which your body burns calories and fat for energy. In addition, the ingredients cause an authentic sense of fullness between meals, so you don’t have those pesky hunger cravings throughout your day.

The PhenGold formula is chock-full of energy-boosting green tea and green coffee, which provide a natural source of caffeine without the harsh side effects. PhenGold also contains L-tyrosine and L-theanine, which are both mood boosters that will give you enhanced mental focus and greater motivation throughout your day.

Here’s the PhenGold ingredient list:

  • 250mg Rhodiola rosea
  • 500mg green tea
  • 100mg green coffee
  • 350mg L-tyrosine
  • 250mg L-theanine
  • 200mg cayenne pepper
  • Vitamins B3, B6, and B12
  • 225mg caffeine
  • 150mg DMAE

PhenGold is one of the best diet pills on our list because it’s 100% safe and all-natural, with no harsh side effects. Every bottle is manufactured right here in the US in facilities registered with the Food and Drug Administration.

Not only does PhenGold cause rapid weight loss, but it’s also non-GMO, vegan-friendly, and contains no artificial substances or fillers. Head to the PhenGold website to check for any discounts or multi-buys to save money. As with most package offers, the more you spend, the more you save.

Click Here for the Lowest Price on PhenGold

5) Trimtone: Best Appetite Suppressant

Even with the best intentions and a ton of motivation, staying on track with your fitness goals can be difficult, especially if you are susceptible to cravings during the day. Enter Trimtone, a fat burner for women that’s one of the best diet supplements for appetite suppression.

Trimtone is a 100% natural fat burner, which can help you burn more calories and prevent those obnoxious hunger cravings from derailing your healthy lifestyle. Here are some more benefits:

Boosts Fat Loss and Burns Calories: Trimtone is thermogenic, which means it kickstarts thermogenesis. Thermogenesis is the process by which your body converts stored fat into energy, stimulating weight loss and helping you burn calories.

Reduces Appetite and Crushes Hunger Cravings: Trimtone is one of the best natural appetite suppressants preventing you from gaining weight due to overeating. The exclusive formula also boosts your metabolic rate and makes you burn calories much faster.

Trimtone is a completely natural weight loss supplement. The ingredients in Trimtone work by stimulating thermogenesis, which gives you the energy boost you need to get through the day without having to take in extra calories.

It’s the best weight loss supplement for women looking to suppress their appetite and lose weight without taking a prescription drug or trying dangerous crash-dieting.

Far too many weight loss supplements on the market today don’t contain all-natural ingredients. Fortunately, Trimtone isn’t one of them. Here are the ingredients:

  • Caffeine
  • Green coffee
  • Green tea
  • Grains of paradise (herb for burning calories)
  • Glucomannan

Trimtone is ideal for women starting on a weight loss journey. Once you begin taking Trimtone, you should see results within a few weeks. Unsurprisingly, combining this weight loss pill with diet and exercise will produce better results than when you take it on its own.

Neither does Trimtone have any harsh side effects. While it does contain 120mg of caffeine, that’s no more than what you would get from a cup of coffee.

Keep in mind, however, that Trimtone is not suitable for vegans or vegetarians because the capsule it comes in is made of gelatin. Check out the Trimtone website to find the most current multi-buys and packages to save money on your order.

Click Here for the Lowest Price on Trimtone

Tips for Choosing the Top Weight Loss Supplements

According to the CDC, 73.6% of American adults over the age of 20 have an overweight or obese body mass index. With such a high number, it should come as no surprise that the market for diet pills is overwhelmingly vast.

In the face of such a large selection, it becomes necessary to spend time researching the best weight loss pills for your body type and health needs. Check out these five factors you should always consider before you make a purchase.

Money-Back Guarantee

Any reputable manufacturer of weight loss supplements should offer a money-back guarantee. For example, most brands will offer a 100-day buy-back guarantee if you purchase more than a three-month supply of pills. Always read the fine print before you buy! That way, you know what your options are if you are unhappy with your purchase.

Natural Ingredients

Reading the list of ingredients is perhaps the most crucial part of your research when considering the best weight loss pill to help you achieve your fitness goals. In addition, always check to ensure that the diet pill you’re about to take doesn’t contain any banned substances or cause adverse side effects.

The Food and Drug Administration has the complete list of banned substances, but here are the most common ones to watch out for:

  • Ephedra
  • Hydroxycut (the actual medication, not the diet pill brand)
  • Clenbuterol (Clen Fat Burner)
  • Sibutramine (a.k.a. Meridia, Sibutrex, and Reductil)
  • Fenfluramine and phentermine (fen-phen is illegal, although phentermine by itself is okay when prescribed by a doctor)

Clean Labels

Do you know how to read supplement labels properly? The FDA regulates weight loss pills but only as dietary supplements, not as food or drugs.

When you’re researching weight loss supplements, avoid any with a label that says “proprietary blend” or “matrix.” A proprietary blend is a unique combination of ingredients, and manufacturers use it as a loophole to hide the exact dosages of each component in the mixture.

For example, let’s say a diet pill has a proprietary blend of five different ingredients that weigh 500mg total. You might assume that each of the five ingredients weighs 100mg. However, that’s not necessarily the case. Technically, the blend could contain 496mg of one ingredient and only a 1mg measure of the others. See the problem?

According to, manufacturers do this so they can use minimal amounts of the most expensive or effective component yet still be able to get away with calling it a “key ingredient.” The takeaway? Look closely at the label and read the fine print before purchasing.

Discounts for Multiple Bottles

Losing weight shouldn’t cost you a ton of cash. Unfortunately, many of the most popular weight loss pills are expensive, and when you need more than a month’s supply, the money can add up quickly. Fortunately, many manufacturers offer discounts on package deals or multi-buys. That means the more you buy, the more money you’ll save.

Brand Reputation

Brand reputation is another critical factor you should consider when buying diet pills. One way to ensure you’re getting a quality product is to do some research before you buy. To start, check Amazon and other e-commerce platforms and read the customer reviews.

If the weight loss pill you’re considering is only available on the manufacturer’s website, then try Googling “[diet pill brand] reviews” and see what comes up. While you may need to dig through a top-heavy list of sponsored results, finding reliable information about any supplement shouldn’t be too difficult.

Understanding the Different Types of Weight Loss Pills

If you’re looking for effective weight loss solutions to enhance your healthy lifestyle, then taking a fat-burning supplement could be the answer. First, however, it’s vital that you understand the different types of weight loss supplements and how they will affect your body.

Exploring potential side effects is particularly important for people with heart problems, breathing issues, or high blood pressure. Here are the four most common types of weight loss products and how they can help people who are overweight reach their body and fitness goals.

Appetite Suppressant

If you often experience irrational hunger cravings throughout the day (even after you’ve just eaten), then appetite suppressants are the best weight loss pills for you. Any diet pill advertised as an appetite suppressant works one of two ways: by curbing hunger cravings or making you feel full even when your stomach is empty or only partially full.

Appetite suppressants are available as both prescription weight loss pills and over-the-counter supplements. According to the Cleveland Clinic, people who take appetite suppressants and combine them with a healthier lifestyle lose an average of 3% to 9% of their starting weight in the first year.

Thermogenic Fat Burner

Thermogenic fat burners work by raising your internal core temperature (just like when you exercise), which increases your metabolic rate to burn more calories and stimulate fat burning. You can easily find thermogenic diet pills over the counter, and most of them contain caffeine as their primary ingredient.

People with heart problems or kidney problems and nursing or pregnant women should avoid taking this type of weight loss pill. Remember that thermogenic diet pills are effective, but they are not a long-term solution for weight loss.

Carb Blockers

Carb blockers work a bit differently than the other types of fat-burning pills on our list. Essentially, they work by blocking the enzymes necessary to digest starch and carbohydrates, which means you can eat carbs without gaining as many calories as you normally would. If you’re taking this type of diet pill, the carbs you eat will travel through your large intestine and exit your body without being digested or absorbed.

Fat Blockers

Fat blockers are a popular type of prescription weight loss drug (e.g., Orlistat) that work in the same way as carb blockers, inhibiting your body’s ability to digest and absorb fat. However, fat blockers don’t help you lose weight. Instead, they limit the amount of dietary fat your body absorbs when you overeat to prevent weight gain.

Taking fat blockers doesn’t mean you can eat whatever you want and never gain weight. No diet pill can do that—not yet, anyway.

The Most Effective Weight Loss Ingredients

Garcinia Cambogia Extract

Garcinia cambogia extract is a natural ingredient that comes from a tropical fruit known as the Malabar tamarind. Purportedly, it contains properties that act as an appetite suppressant and fat blocker.

The Garcinia cambogia extract contains the active ingredient hydroxycitric acid (HCA). While you won’t find much scientific research on the effectiveness of HCA as a weight loss aid, it does raise serotonin (a natural appetite suppressant) and may block certain fat-producing enzymes.

Raspberry Ketones

Despite the name “raspberry ketone,” this natural substance comes from many fruits and vegetables, including berries, grapes, apples, peaches, kiwi, rhubarb, and even pine tree bark. While the jury is still out on whether raspberry ketones are an effective weight loss aid, some research shows that they boost animal metabolism.

Unfortunately, there’s not a lot of research showing whether they will also cause the same boost in humans. So, while it may not be the most effective ingredient, it’s not harmful and won’t cause any adverse side effects beyond what you might feel after drinking a cup of coffee.

Green Coffee Bean Extract

Green coffee beans aren’t any different from the brown ones that go in your cup o’ joe. However, there is one fundamental difference: green coffee beans don’t go through the roasting process, so they remain green instead of turning brown.

Fresh coffee beans contain chlorogenic acid, a substance with antioxidant properties that may lower blood pressure and help you lose weight. Unfortunately, the roasting process removes the chlorogenic acid, rendering the beans useless for weight loss but perfect for a latte. Generally, green coffee beans can cause the same side effects as caffeine, like shakiness or a slight headache.


Glucomannan has exploded in popularity over the last few years as a natural ingredient in diet supplements. This dietary fiber comes from a root vegetable called the elephant yam or konjac.

Glucomannan is incredibly absorbent, so it swells in your stomach, causing you to feel fuller for longer. It also works to slow down the rate at which your stomach empties and lowers your protein and fat absorption rate. When taken before meals, it provides weight loss benefits like curbing your appetite and preventing overeating.

Green Tea Extract

Green tea extract is another common ingredient you’ll find in weight loss drugs because research has shown its effectiveness as an aid for losing weight and lowering blood pressure. Plus, it’s chock-full of antioxidants and other beneficial compounds. This delicious tea is a natural way to lose weight healthily and provides numerous benefits:

  • Contains substances that boost metabolism (like caffeine and EGCG)
  • Increases fat burning during exercise
  • Raises the metabolic rate to burn more calories
  • Enhances the effect of the body’s natural fat-burning hormones
  • Suppresses appetite and curbs cravings
  • Reduces stubborn belly fat

Conjugated Linoleic Acid (CLA)

Conjugated linoleic acid (CLA) is another one of the most common natural ingredients you’ll find in dietary supplements for weight loss. It comes from grazing animals like cows and deer, which have a digestive enzyme in their gut that converts omega-6 fatty acids from the plants they eat into CLA.

Research has shown that CLA is a highly effective weight loss aid for animals. Unfortunately, that’s not the case with humans. One study found that humans taking 3.2g of CLA per day only lost half a pound more per month than those taking placebos.

How to Get the Best Results with a Weight Loss Supplement

If you’re considering starting a supplement regimen, you probably want to know how to get the best results from your diet pills. Please remember, you won’t be able to take a pill and magically lose weight. In reality, it takes hard work and commitment. A weight-loss journey is no simple thing, and if it were that easy, everybody would look like a supermodel.

First, you’ll need to practice moderation in all things. Eat a well-balanced diet and reduce your alcohol consumption and calorie intake, and if you’re a smoker, it’s time to quit. Next, you’ll need to start an exercise program. If that sounds daunting, just start slow and work your way up. Whether you like cardio, Pilates, Zumba, martial arts, or something else entirely, find a way to keep your body moving.

Finally, if you’re on medication, always consult with your doctor before starting a new supplement regimen to ensure it won’t cause harmful side effects. However, by eating a healthy, well-balanced diet, exercising, and making good decisions regarding your health, you can enhance the effectiveness of your pills for the best possible results.

Frequently Asked Questions About Weight Loss Pills

What Is the Best Weight Loss Pill to Lose Belly Fat?

If you have stubborn belly fat that won’t disappear even though you’re eating healthy and exercising, then the best weight loss pill you can take is PhenQ. Not only is PhenQ an effective fat burner, but it also stops the production of new fat and curbs hunger cravings at the same time.

Do Diet Pills Have Any Side Effects?

Yes, some weight loss pills can have harsh side effects. Usually, side effects are only a problem with products that contain high levels of stimulants. If you’ve ever had too many cups of coffee, then you know the side effects we’re talking about: headache, shakiness, feeling jittery, etc. Depending on the ingredients, some weight loss pills can also cause side effects like dizziness, dry mouth, or an upset stomach.

What Type of Weight Loss Supplement Is Best?

The answer to this question varies on your preference, body type, overall health, and fitness goals, to name a few. Spend some time considering those factors before you start your research. As for the five products on our list, PhenQ is one of the best weight loss pills for general purposes.

When Should You Consider Prescription Weight Loss Drugs?

If you have been eating healthy, exercising regularly, and taking a fat loss supplement but you have yet to see results, you may want to consider going to a doctor for a prescription weight loss drug. Prescriptions may also be ideal for people with genetic predispositions for obesity or other health conditions that make losing weight difficult.

How Fast Do Weight Loss Pills Work?

Every weight loss pill works differently, and your results will vary based on your body type, lifestyle, overall health, etc. Some can help you lose water weight within a few days; others may take a month or even six months to show optimal results. However, you can speed up your results by combining your supplement regimen with diet and exercise.

Are Any Weight Loss Pills Guaranteed to Work?

As with any drug, there’s no guarantee that you’ll get the amazing results you want when taking a weight loss medication. Whether your doctor prescribes you a weight loss drug or you take an OTC product, you should combine it with exercise, well-balanced foods, and a healthy lifestyle to see the best possible results. Long-term prescriptions (over 12 weeks) can result in significant weight loss, usually between 3% and 7% of total body weight from your starting point.

Are Weight Loss Pills FDA Approved?

No, dietary supplements do not require FDA approval before they go on the market. However, the FDA requires manufacturers to ensure their products are safe, free of banned substances, and have an accurate label with the complete ingredient list.

Is Hydroxycut Good for Weight Loss?

Yes, the brand Hydroxycut is an effective supplement for burning fat and reducing your weight. It’s a thermogenic fat burner that boosts metabolism and increases energy.

However, the weight management drug Hydroxycut (not the brand) is an FDA-banned substance that can cause harmful side effects. Be sure to read the label of every supplement before you buy it to ensure it doesn’t contain the dangerous banned substances we listed earlier.

Final Thoughts

Hopefully, our review of the best weight loss pills available on the market has given you some valuable information to help you with your decision. The key takeaways here: always do your research, read the label, and make sure you combine your weight loss supplement with a good diet and an appropriate amount of exercise for the best results. For those of you just starting on your weight loss journey, work hard and don’t give up!