Phentermine Over-The-Counter: 4 Best Natural OTC Phentermine Alternatives to Buy in 2022

Over-The-Counter: 4 Best Natural OTC Phentermine Alternatives to Buy in 2022
Over-The-Counter: 4 Best Natural OTC Phentermine Alternatives to Buy in 2022 [ Photo ]
Published Dec. 28, 2021|Updated Dec. 28, 2021

Most people want to lose weight, either for health, fitness, or aesthetic reasons. Weight loss can be frustrating, especially when you’re doing everything right but still hit a plateau and the scale refuses to budge.

Phentermine is a weight-loss drug, developed in the 1950s, that has been incredibly popular as the go-to weight loss aid. However, due to its potential side effects and the need for a doctor’s prescription, many people are turning to natural phentermine alternatives for weight loss.

We’ve reviewed the best phentermine alternatives on the market to see which products work the best. We evaluated each OTC phentermine substitute on a variety of factors including ingredients, reviews, effectiveness, and price.

If you’re ready to accelerate your weight loss journey, here are the best over-the-counter phentermine alternatives to buy in 2022.

The 4 Best Phentermine Alternatives to Buy Online in 2022

#1. PhenQ: Best Weight Loss Pill Overall

PhenQ is the flagship product of Wolfson Berg Limited, a dietary supplement company that began in 2005. Since then, PhenQ has become one of the most popular phentermine over-the-counter (OTC) alternatives, offering a multi-pronged approach to healthy weight loss.

According to the manufacturer, PhenQ has numerous benefits, including:

  • Appetite suppression, making it easier to stick to your diet and avoid food cravings.
  • Blocking of fat production, allowing you to keep the weight off once you’ve reached your ideal body weight.
  • Boosting of mood and energy levels that bypass the adverse side effects of restricted-calorie diets.

How it Works

PhenQ works in two main ways: first, by helping you burn through fat more quickly, and secondly, by preventing the accumulation of new body fat. PhenQ also contains natural appetite suppressants that reduce cravings and ensure that you stick to your diet and exercise plan.

Wolfson Berg Limited claims that PhenQ can cut your body fat by up to 7.24% while increasing lean muscle mass at the same time.

Formula Overview

PhenQ’s natural formula contains six ingredients aimed at boosting weight loss. These include:

L-Carnitine Fumarate: This amino acid derivative promotes the conversion of stored fat into energy. Not only does this help you lose fat faster, but it also boosts energy to help you avoid diet-related fatigue.

Anhydrous Caffeine: A natural stimulant, caffeine helps with focus and mental acuity while also boosting energy.

α-Lacys Reset: A combination of α-lipoic acid, cysteine, and magnesium, this compound boosts metabolism and increases body heat, which forces your body to burn fat faster to maintain the slightly higher core temperature.

Nopal Extract: Nopal provides the primary source of fiber, which helps promote a feeling of fullness while reducing the risk of additional fluid retention.

Capsimax: A combination of capsicum, piperine, niacin (vitamin B3), and caffeine, piperine blocks new fat production, while capsicum raises your body temperature and triggers thermogenesis. The other ingredients help maintain energy levels and overall health.

Chromium Picolinate: This mineral derivative reduces sugar cravings and overall appetite, making it easier to avoid those tasty treats hidden in the cupboard.

Who Is This Product Best For?

PhenQ is a suitable option for anyone looking to lose weight, but it’s unsuitable for pregnant or nursing women. PhenQ is also 100% vegan and gluten-free, making it the first choice for individuals with dietary restrictions.

The manufacturer offers a 60-day money-back guarantee for every purchase and free worldwide shipping. You can also get massive discounts if you buy multiple bottles at once.

Click Here for the Lowest Price on PhenQ

#2. PrimeShred: Best Diet Pills for Men

Manufactured in the U.K., this weight loss pill claims to promote weight loss while also helping you retain your muscle mass. PrimeShred’s primary market is gym-goers looking to lose fat to get a “shredded” look and who have hit a plateau where a good diet doesn’t work anymore.

PrimeShred advertises several benefits, including fat loss without a corresponding loss in muscle or strength gains. The supplement also claims to boost mental and physical energy, helping users push past the final hurdle towards their ideal body goals.

How it Works

PrimeShred uses a wide range of natural weight-loss ingredients common in all good OTC phentermine alternatives. It takes a three-pronged approach to losing weight that involves:

  • Promoting thermogenesis, or increasing body heat, which speeds up your metabolic rate and forces your body to burn calories faster.
  • Activating various hormones in your body that control hunger and fat burning.
  • Providing a mental and energy boost to avoid the brain fog commonly associated with a low-calorie diet.

Formula Overview

In addition to common natural ingredients found in other diet pills, such as caffeine, green tea extract, and capsicum extract, PrimeShred contains several nootropics and additional ingredients that boost the pill’s weight loss potential.

Some notable ingredients include:

Rhodiola Rosea Root Extract: A powerful adaptogen, this extract helps you cope with physical and mental stress.

Dimethylethanolamine (DMAE): A choline precursor, DMAE can potentially boost mood and enhance brain function and memory.

L-Tyrosine: An important amino acid involved in the production of melanin and thyroid hormones, tyrosine supplementation may help with improved alertness and mood.

Green Coffee Bean Extract: Roasting coffee beans removes many organic compounds, which is why PrimeShred uses pre-roasted green coffee beans instead. This extract contains caffeine and other compounds that can potentially increase thermogenesis and boost metabolism, leading to more fat loss.

Who Is This Product Best For?

While anyone can benefit from these weight loss pills, they’re best for people looking to lose that final bit of fat and finally achieve their ideal physique.

The manufacturers of PrimeShred have enough faith in their product to offer a 100-day money-back guarantee. The company also offers free worldwide shipping, is 100% vegan friendly, and contains no GMOs, gluten, soy, or dairy.

Click Here for the Lowest Price on PrimeShred

#3. Leanbean: Natural Phentermine Alternative Without A Prescription

Unlike many fat burners, LeanBean doesn’t rely on stimulants for its weight loss properties. Instead, it uses a dedicated blend of 11 natural metabolism boosters to prevent weight gain and kickstart the fat-burning process.

LeanBean markets itself to women looking to lose weight and enjoy many weight loss benefits, such as a toned body and increased energy.

According to the manufacturer, LeanBean reduces your calorie intake by suppressing your appetite. It supports and promotes fat metabolism to burn extra calories while also having a specialized vitamin complex to promote a clean, jitter-free energy boost.

How it Works

LeanBean bases its ingredients list on recent research showing that men and women experience food cravings differently.

The supplement provides a precisely tailored mix of ingredients that help women improve their metabolism, combat cravings, and suppress appetite to improve diet adherence.

Formula Overview

LeanBean contains a special mix designed for successful weight loss without the unpleasant effects of stimulants like caffeine. The product contains:

Glucomannan is one of the best appetite suppressants that helps you stick to a low-calorie diet and avoid cravings that lead to weight gain.

Choline is an important nutrient involved in cell membrane formation, central nervous system function, muscle control, and lipid transport and metabolism. It’s an essential nutrient, which means that you need to get it from your diet or through dietary supplements.

Vitamins B6 and B12: B-vitamins are essential for the normal nervous system function. Many people on a calorie-restricted diet don’t get enough nutrients, leading to brain fog and a feeling of malaise. Including a Vitamin B complex ensures that you retain your energy levels during your weight loss journey.

Chromium Picolinate is an essential trace mineral that is vital in metabolic function. It assists the body in maintaining normal glucose levels, even during heavy calorie restriction, preventing the brain fog commonly associated with dieting.

Who Is This Product Best For?

LeanBean is one of the most effective phentermine alternatives for women looking to lose weight. It uses appetite suppressants that work best for women while also offering a host of additional ingredients specifically designed to support women looking for a natural weight reduction solution.

LeanBean has a 90-day money-back guarantee and free global shipping on its Complete Bundle package.

Click Here for the Lowest Price on Leanbean

#4. PhenGold: Best Appetite Suppressant

PhenGold comes from manufacturer Swiss Research Labs Ltd., the same company that makes all-natural supplements like Zotrim and TrimTone.

As an established supplement manufacturer, Swiss Research Labs, Ltd has the resources and facilities to provide high-grade, reliable weight loss supplements that are excellent alternatives to phentermine.

The product advertises multiple weight loss benefits such as improved energy, faster metabolism, and excellent appetite suppression. It works for both men and women and uses only natural ingredients to provide its desired results.

How it Works

PhenGold uses an array of natural ingredients known to help with weight management. These ingredients include an appetite suppressant, thermogenic boosters to burn extra calories, and supporting compounds to maintain mood and energy.

Formula Overview

The key ingredients in PhenGold include:

Green Tea Extract: Rich with antioxidants, minerals, and caffeine, green tea extra is an effective appetite suppressant that also increases energy and boosts body heat production.

Green Coffee Extract: This unprocessed extract contains important nutrients such as chlorogenic acid that reduces fat absorption, helping with weight maintenance.

L-Theanine: An important adaptogen, this compound can reduce stress and anxiety, both of which contribute to excess weight.

Cayenne Pepper helps the body absorb important nutrients and acts as a metabolism booster.

DMAE is a nootropic substance that boosts energy and improves mood, memory, and brain function.

Vitamin B Complex is a mix of vitamins that help maintain a healthy metabolism and nervous system.

The product also contains several other extracts and supporting ingredients to enhance the effects of the key ingredients.

Who Is This Product Best For?

PhenGold is a good choice for anyone looking to dip their toe into the world of weight loss supplements and lose weight. It’s suitable for people of all ages and genders who want a safe phentermine substitute.

PhenGold’s website often has special deals, such as a “buy three, get two extra” promotion that can help you save money. The product has a 100-day money-back promise if you buy a two- or three-month supply.

Click Here for the Lowest Price on PhenGold

What Is Phentermine and How Does it Help with Weight Loss?

Phentermine is a compound closely related to amphetamine. It is a Schedule IV controlled substance in the U.S., which means it has a potential for abuse. It stimulates the central nervous system, decreases your appetite, and raises your heart rate and blood pressure. The elevated heart rate stimulates your metabolism and elevates your basal metabolic rate (BMR).

The drug works mainly as an appetite suppressant supplement. If you don’t feel hungry, you won’t get strong cravings and cave in to pressure while on a diet. Some people experience such a strong effect that they even forget to eat, which is one of the reasons why phentermine can be extremely dangerous.

Doctors formerly recommended phentermine diet pills to patients with a dangerous body mass index due to its reputation as a potent appetite suppressant and metabolism booster.

However, due to its addictive nature and dangerous side effects, phentermine has lost popularity as a prescription weight loss medication. The U.S. Food and Drug Administration warns doctors that “The limited usefulness of [this substance] should be measured against possible risk factors inherent in their use.”

The rise of other prescription medications and interventions has led to a massive decline of phentermine prescriptions, and even today, doctors only prescribe its use under strict medical supervision.

How We Ranked the Top Phentermine Alternatives

Since phentermine is a risky prescription medication, we looked at various over-the-counter alternatives instead.

As many of these OTC phentermine alternatives are supplements and not FDA-approved weight loss medications, finding effective and reputable diet pills can be a huge challenge. We used a set of four criteria when we looked at various diet pills to determine whether they might be worth your time and money.


Many natural ingredients possess proven appetite suppressant, thermogenic, or energy-boosting properties, including caffeine, guarana, and capsicums.

When looking for the best natural phentermine alternative, we looked at the ingredient combination as well as the dosages of the various ingredients.

Most diet pills use a combination of ingredients to tackle weight loss in various ways. Many compounds have synergistic effects, meaning they’re more effective when used together. They will combine boosting metabolism with appetite suppression, aiming for you to burn more calories in a day than you consume.

The dose of an active ingredient is just as important as the ingredient itself. In most cases, the more of an active ingredient you get, the better the final result. However, be careful with stimulants like caffeine - some people have lower tolerances, and a high-caffeine OTC phentermine alternative may make you feel jittery and sick.

Advertised Benefits

Many people have had negative experiences with diet pills, which often promise unrealistic results and fail to deliver. Any over-the-counter diet that promises you’ll shed 30 pounds in a week is lying, no matter how high your initial body weight is.

A natural over-the-counter phentermine pill will never have a dramatic effect, mainly due to the subtle effects of the ingredients.

In many cases, a delicate balance exists between effectiveness and side effects since many of the side effects directly result from the active ingredients. Instead, it’s better to view the phentermine OTC alternative as a boost to your existing diet and exercise plan.


Looking at reviews is a good way to estimate the potential effectiveness of a particular weight loss supplement. Make sure to look at trends since there will always be individual outliers that have either a great or very poor experience with any product.

When it comes to any phentermine over-the-counter diet pill, remember that diet and exercise play an important role in the end result. Try to look at reviews that have a similar exercise and diet profile to yours, which will give you a good guideline on the types of results you can expect.

Price and Guarantee

Unlike FDA-regulated prescription medication, most diet pills are unregulated and untested. Plenty of unscrupulous manufacturers will lie about their miracle diet pill and fail to include any active ingredients in their products to keep costs low.

Often, a very cheap diet pill will contain nothing but filler. Instead, opt for more expensive alternatives from reputable manufacturers. Most manufacturers will offer at least a 60-day money-back guarantee and will refund your purchase if you aren’t satisfied.

How Do Natural Alternatives Compare to Phentermine?

The truth is that no phentermine HCl alternative will produce the same kind of results as the original pill. Most natural products produce a more subtle effect.

This subtle effect isn’t a bad thing, as it also means that a significantly smaller chance of any hazardous side effects exists. Even the most potent natural phentermine alternative will only produce effects associated with a caffeine overdose, such as headaches and nausea.

It’s a good idea to view natural alternatives as a supplement to your existing healthy diet and exercise plan. You won’t lose weight without putting the effort in, but the supplement can give you a much-needed boost to give you the results you want.

The Potential Risks of Prescription Phentermine

Just like other medications, prescription phentermine comes with a long list of potential risks and side effects. While these side effects don’t occur in most patients, they can still significantly impact those who do experience them.

Common side effects associated with phentermine include:

  • High blood pressure
  • Dizziness
  • Dry mouth
  • Nausea
  • Irritability
  • Mental/mood changes
  • Uncontrolled anger
  • Uncontrolled muscle movements
  • Nervousness
  • Vision changes

Phentermine can also produce several very dangerous interactions with other drugs. It can interact with other weight loss pills to cause a potentially fatal lung disorder known as pulmonary hypertension. It also interacts with duloxetine and other SSRIs and MAO inhibitors.

Frequently Asked Questions

Can You Buy Real Phentermine Over the Counter?

No, pharmacies will require a prescription for phentermine.

Can You Buy Phentermine Online?

While it’s possible to buy phentermine online, it’s illegal to do so. Trying to buy real phentermine may result in your purchase of counterfeit products that either don’t work or are actively harmful to your health.

If you can’t get a prescription for phentermine, stick to natural alternatives from a reputable manufacturer.

Does Phentermine Work for Weight Loss?

Yes, it works very well. Unfortunately, the side effects of using the drug can be very severe, and doctors will only recommend it in individuals with serious weight and health concerns and only on a very short-term basis.

While alternatives may not have the same level of effectiveness, they are much safer and are still effective enough to be worth your time.

How Much Do Phentermine Substitutes Cost?

Prices for phentermine substitutes can vary dramatically. The ones we’ve reviewed tend to cost around $60 for a month’s supply. However, most companies will have specials to enable you to get significant discounts if you order multiple products at once.

Some of the most cost-effective choices are any “buy three months and get two months free” promotions, which can save you almost 50% on the price of an individual bottle.

Final Thoughts

Everyone wants a miracle pill that will let them shed pounds of fat without having to change their diet or exercise plan. The truth is that many of the most effective weight loss aids have serious side effects and can have lasting consequences on your wellbeing. Furthermore, once you stop using them, you’ll put the weight back on quickly.

Phentermine is a potent and effective weight loss drug. However, it can be addictive or damaging to your health, which is why doctors will actively weigh the benefits of using the drug against its drawbacks before deciding whether it’s the right option for you.

Most phentermine alternatives use ingredients that mimic the effects of phentermine without the serious drawbacks. They’re relatively effective and, if used correctly, can help you achieve your goals. However, no drug can be a substitute for diet or exercise. They can only boost your progress.

Finding the best alternative to phentermine can also be challenging. All of the products we reviewed come from reputable manufacturers and have satisfied customers reporting on their effectiveness.

If you’re interested in finding the right weight loss supplement, our choices, above, are a helpful place to start.


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